Problem:
Windows Vista. Fuzzy, small, unreadable text in certain programs when windows Aero is enabled. However when you disable the Vista Aero theme and apply the Basic theme, the text is clear.
Hardware/Settings: High resolution monitor, High Font DPI Scaling, Vista Aero Theme.
Effected programs: Adobe Photoshop Help menu, OpenOffice 2.0
Solution:
Right click desktop - Personalize - Adjust Font Size - Custom DPI - USE WINDOWS XP STYLE FONT SCALING - check that box
You now have readable text, while enjoying the Vista Aero UI on your high res monitor.